Translational Bioinformatics Translational Bioinformatics and Drug Discovery The greatest challenge of the postgenomic era is to understand the function of genes and gene products in multiple organisms Molecular Chaperones and Cancer Research Our research is focused on the development and integration of computational and experimental approaches for high-throughput ligand screening and design Protein Kinases and Cancer Research Protein kinase genes are signaling switches with a conserved catalytic domain that phosphorylate protein substrates and play a critical role Computational Cancer Biology The challenge of understanding biological systems at the molecular and systems level as well as the integration of computational and Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins. Stetz G1, Verkhivker GM1,2. Author information 1 Graduate Program in Computational and Data Sciences, Schmid College of Science and Technology,